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Branched-Selective Direct α-Alkylation of Cyclic Ketones with Simple Alkenes

Herein, we describe an intermolecular direct branched-selective α-alkylation of cyclic ketones with simple alkenes as the alkylation agents. Through an enamine-transition metal cooperative catalysis mode, the α-alkylation is realized in an atom- and step-economic manner with excellent branched selec...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Xing, Dong, Qi, Xiaotian, Marchant, Daniel, Liu, Peng, Dong, Guangbin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604859/
https://ncbi.nlm.nih.gov/pubmed/30707491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201900301
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