Gut microbe-derived metabolite trimethylamine N-oxide activates the cardiac autonomic nervous system and facilitates ischemia-induced ventricular arrhythmia via two different pathways

BACKGROUND: We previously demonstrated the gut microbes-derived metabolite trimethylamine N-oxide (TMAO) could activate the atrial autonomic ganglion plexus and promote atrial arrhythmia. The cardiac sympathetic nervous system (CSNS) play important roles in modulating ventricular arrhythmia (VA). ME...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EBioMedicine
Päätekijät: Meng, Guannan, Zhou, Xiaoya, Wang, Menglong, Zhou, Liping, Wang, Zhenya, Wang, Meng, Deng, Jielin, Wang, Yuhong, Zhou, Zhen, Zhang, Yifeng, Lai, Yanqiu, Zhang, Qianqian, Yang, Xiaomeng, Yu, Lilei, Jiang, Hong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2019
Aiheet:
Research paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603492/
https://ncbi.nlm.nih.gov/pubmed/30954457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.066
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