Gut microbe-derived metabolite trimethylamine N-oxide activates the cardiac autonomic nervous system and facilitates ischemia-induced ventricular arrhythmia via two different pathways

BACKGROUND: We previously demonstrated the gut microbes-derived metabolite trimethylamine N-oxide (TMAO) could activate the atrial autonomic ganglion plexus and promote atrial arrhythmia. The cardiac sympathetic nervous system (CSNS) play important roles in modulating ventricular arrhythmia (VA). ME...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:EBioMedicine
मुख्य लेखकों: Meng, Guannan, Zhou, Xiaoya, Wang, Menglong, Zhou, Liping, Wang, Zhenya, Wang, Meng, Deng, Jielin, Wang, Yuhong, Zhou, Zhen, Zhang, Yifeng, Lai, Yanqiu, Zhang, Qianqian, Yang, Xiaomeng, Yu, Lilei, Jiang, Hong
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2019
विषय:
Research paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603492/
https://ncbi.nlm.nih.gov/pubmed/30954457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.066
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