Asymmetric Division Gene Neurl2 Mediates Twist2 Regulation of Self-Renewal of Mouse Lewis Lung Cancer Stem Cells

Cancer stem cells (CSCs) play an important role in tumor development. While Epithelial-Mesenchymal Transition (EMT) has been shown to promote CSC self-renewal, underlying mechanisms are unclear. Here we identified and characterized the requirement of twist2, the EMT transcription factor, for the reg...

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Bibliographische Detailangaben
Veröffentlicht in:J Cancer
Hauptverfasser: Liu, Doudou, Xing, H. Rosie, Liu, Yongli, Sun, Zhiwei, Ye, Ting, Li, Jingyuan, Wang, Jianyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603408/
https://ncbi.nlm.nih.gov/pubmed/31293641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.31553
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