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Transcriptional Activation of Gstp1 by MEK/ERK Signaling Confers Chemo-Resistance to Cisplatin in Lung Cancer Stem Cells

Lung cancer management remains a challenge due to its asymptomatic and late presentation when it is metastatic. The clinical response to the first-line platinum-based chemotherapy in patients with advanced lung cancer is disappointing due to the development of chemoresistance. Chemoresistance is a c...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Front Oncol
मुख्य लेखकों: Li, Jingyuan, Ye, Ting, Liu, Yongli, Kong, Liangsheng, Sun, Zhiwei, Liu, Doudou, Wang, Jianyu, Xing, H. Rosie
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584806/
https://ncbi.nlm.nih.gov/pubmed/31263672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00476
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