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Autophagy augments the self-renewal of lung cancer stem cells by the degradation of ubiquitinated p53

It has been postulated that cancer stem cells (CSCs) are involved in all aspects of human cancer, although the mechanisms governing the regulation of CSC self-renewal in the cancer state remain poorly defined. In the literature, both the pro- and anti-oncogenic activities of autophagy have been demo...

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Bibliografski detalji
Izdano u:Cell Death Dis
Glavni autori: Wang, Jianyu, Liu, Doudou, Sun, Zhiwei, Ye, Ting, Li, Jingyuan, Zeng, Bin, Zhao, Qiting, Rosie Xing, H.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815724/
https://ncbi.nlm.nih.gov/pubmed/33468994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03392-6
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