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Autophagy augments the self-renewal of lung cancer stem cells by the degradation of ubiquitinated p53

It has been postulated that cancer stem cells (CSCs) are involved in all aspects of human cancer, although the mechanisms governing the regulation of CSC self-renewal in the cancer state remain poorly defined. In the literature, both the pro- and anti-oncogenic activities of autophagy have been demo...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Wang, Jianyu, Liu, Doudou, Sun, Zhiwei, Ye, Ting, Li, Jingyuan, Zeng, Bin, Zhao, Qiting, Rosie Xing, H.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815724/
https://ncbi.nlm.nih.gov/pubmed/33468994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03392-6
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