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Accelerated podocyte detachment early after kidney transplantation is related to long-term allograft loss of function

BACKGROUND: Kidney allograft half-life has not improved despite excellent short-term survival. Recent long-term surveillance biopsy studies identify accumulating glomerulosclerosis (GS) to be associated with late allograft loss. While podocyte depletion is well known to drive proteinuria and GS in a...

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Vydáno v:Nephrol Dial Transplant
Hlavní autoři: Naik, Abhijit S, Afshinnia, Farsad, Aqeel, Jawad, Cibrik, Diane M, Samaniego, Milagros, Wickman, Larysa, Wang, Su Q, Chowdhury, Mahboob, Wiggins, Roger C
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603364/
https://ncbi.nlm.nih.gov/pubmed/30500951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfy350
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