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FSGS as an Adaptive Response to Growth-Induced Podocyte Stress

Glomerular sclerotic lesions develop when the glomerular filtration surface area exceeds the availability of podocyte foot process coverage, but the mechanisms involved are incompletely characterized. We evaluated potential mechanisms using a transgenic (podocin promoter-AA-4E-BP1) rat in which podo...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Nishizono, Ryuzoh, Kikuchi, Masao, Wang, Su Q., Chowdhury, Mahboob, Nair, Viji, Hartman, John, Fukuda, Akihiro, Wickman, Larysa, Hodgin, Jeffrey B., Bitzer, Markus, Naik, Abhijit, Wiggins, Jocelyn, Kretzler, Matthias, Wiggins, Roger C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619973/
https://ncbi.nlm.nih.gov/pubmed/28720684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017020174
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