FSGS as an Adaptive Response to Growth-Induced Podocyte Stress

Glomerular sclerotic lesions develop when the glomerular filtration surface area exceeds the availability of podocyte foot process coverage, but the mechanisms involved are incompletely characterized. We evaluated potential mechanisms using a transgenic (podocin promoter-AA-4E-BP1) rat in which podo...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Nishizono, Ryuzoh, Kikuchi, Masao, Wang, Su Q., Chowdhury, Mahboob, Nair, Viji, Hartman, John, Fukuda, Akihiro, Wickman, Larysa, Hodgin, Jeffrey B., Bitzer, Markus, Naik, Abhijit, Wiggins, Jocelyn, Kretzler, Matthias, Wiggins, Roger C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2017
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619973/
https://ncbi.nlm.nih.gov/pubmed/28720684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017020174
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