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FSGS as an Adaptive Response to Growth-Induced Podocyte Stress

Glomerular sclerotic lesions develop when the glomerular filtration surface area exceeds the availability of podocyte foot process coverage, but the mechanisms involved are incompletely characterized. We evaluated potential mechanisms using a transgenic (podocin promoter-AA-4E-BP1) rat in which podo...

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Bibliografiske detaljer
Udgivet i:J Am Soc Nephrol
Main Authors: Nishizono, Ryuzoh, Kikuchi, Masao, Wang, Su Q., Chowdhury, Mahboob, Nair, Viji, Hartman, John, Fukuda, Akihiro, Wickman, Larysa, Hodgin, Jeffrey B., Bitzer, Markus, Naik, Abhijit, Wiggins, Jocelyn, Kretzler, Matthias, Wiggins, Roger C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619973/
https://ncbi.nlm.nih.gov/pubmed/28720684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017020174
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