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Accelerated podocyte detachment and progressive podocyte loss from glomeruli with age in Alport Syndrome
Podocyte depletion is a common mechanism driving progression in glomerular diseases. Alport Syndrome glomerulopathy, caused by defective α3α4α5 (IV) collagen heterotrimer production by podocytes, is associated with an increased rate of podocyte detachment detectable in urine and reduced glomerular p...
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| Publicado no: | Kidney Int |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5696060/ https://ncbi.nlm.nih.gov/pubmed/28754557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2017.05.017 |
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