An one-pot two-step automated synthesis of [(18)F]T807 injection, its biodistribution in mice and monkeys, and a preliminary study in humans

[(18)F]T807 is a potent tau protein imaging agent. In order to fulfill the demand from preclinical and clinical studies, we developed an automated one-pot two-step synthesis of this potent tau imaging agent and studied its stability, and dosimetry in mice and monkeys. We also conducted a preliminary...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Huang, Ya-Yao, Chiu, Ming-Jang, Yen, Ruoh-Fang, Tsai, Chia-Ling, Hsieh, Hao-Yu, Chiu, Ching-Hung, Wu, Chi-Han, Hsin, Ling-Wei, Tzen, Kai-Yuan, Cheng, Cheng-Yi, Ma, Kuo-Hsing, Shiue, Chyng-Yann
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602418/
https://ncbi.nlm.nih.gov/pubmed/31260447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217384
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares