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Toxicity and radiation dosimetry studies of the serotonin transporter radioligand [(18) F]AFM in rats and monkeys

BACKGROUND: [(18) F]AFM is a potent and promising PET imaging agent for the serotonin transporter. We carried out an acute toxicity study in rats and radiation dosimetry in monkeys before the translation of the tracer to humans. METHODS: Single- and multiple-dose toxicity studies were conducted in S...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EJNMMI Res
Päätekijät: Huang, Ya-Yao, Cheng, Chen-Yi, Huang, Wen-Sheng, Ma, Kuo-Hsing, Tseng, Ta-Wei, Chou, Ta-Kai, Huang, Yiyun, Shiue, Chyng-Yann
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Berlin Heidelberg 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452647/
https://ncbi.nlm.nih.gov/pubmed/26116128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-014-0071-1
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