Toxicity and radiation dosimetry studies of the serotonin transporter radioligand [(18) F]AFM in rats and monkeys

BACKGROUND: [(18) F]AFM is a potent and promising PET imaging agent for the serotonin transporter. We carried out an acute toxicity study in rats and radiation dosimetry in monkeys before the translation of the tracer to humans. METHODS: Single- and multiple-dose toxicity studies were conducted in S...

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Vydáno v:EJNMMI Res
Hlavní autoři: Huang, Ya-Yao, Cheng, Chen-Yi, Huang, Wen-Sheng, Ma, Kuo-Hsing, Tseng, Ta-Wei, Chou, Ta-Kai, Huang, Yiyun, Shiue, Chyng-Yann
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2014
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452647/
https://ncbi.nlm.nih.gov/pubmed/26116128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-014-0071-1
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