Toxicity and radiation dosimetry studies of the serotonin transporter radioligand [(18) F]AFM in rats and monkeys

BACKGROUND: [(18) F]AFM is a potent and promising PET imaging agent for the serotonin transporter. We carried out an acute toxicity study in rats and radiation dosimetry in monkeys before the translation of the tracer to humans. METHODS: Single- and multiple-dose toxicity studies were conducted in S...

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Publicat a:EJNMMI Res
Autors principals: Huang, Ya-Yao, Cheng, Chen-Yi, Huang, Wen-Sheng, Ma, Kuo-Hsing, Tseng, Ta-Wei, Chou, Ta-Kai, Huang, Yiyun, Shiue, Chyng-Yann
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2014
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452647/
https://ncbi.nlm.nih.gov/pubmed/26116128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-014-0071-1
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