α-synuclein interaction with zero-valent iron nanoparticles accelerates structural rearrangement into amyloid-susceptible structure with increased cytotoxic tendency

AIM: It has been indicated that NPs may change the amyloidogenic steps of proteins and relevant cytotoxicity. Therefore, this report assigned to explore the impact of ZVFe NPs on the amyloidogenicity and cytotoxicity of α-synuclein as one of the many known amyloid proteins. METHODS: The characteriza...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Tahaei Gilan, Seyedeh Sahar, Yahya Rayat, Dorsa, Mustafa, Twana Ahmed, Aziz, Falah Mohammad, Shahpasand, Koorosh, Akhtari, Keivan, Salihi, Abbas, Abou-Zied, Osama K, Falahati, Mojtaba
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2019
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602305/
https://ncbi.nlm.nih.gov/pubmed/31417259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S212387
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi