Amorphous aggregation of tau in the presence of titanium dioxide nanoparticles: biophysical, computational, and cellular studies

BACKGROUND: Nanoparticles (NPs) when injected into the body can reach target tissues like nervous system and interact with tau proteins and neurons. This can trigger conformational changes of tau and may affect NP toxicity. METHODS: In this study, we used several biophysical techniques (extrinsic an...

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Detalles Bibliográficos
Publicado en:Int J Nanomedicine
Main Authors: Fardanesh, Aida, Zibaie, Sedigheh, Shariati, Behdad, Attar, Farnoosh, Rouhollah, Fatemeh, Akhtari, Keivan, Shahpasand, Koroosh, Saboury, Ali Akbar, Falahati, Mojtaba
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2019
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362919/
https://ncbi.nlm.nih.gov/pubmed/30774341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S194658
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