α-synuclein interaction with zero-valent iron nanoparticles accelerates structural rearrangement into amyloid-susceptible structure with increased cytotoxic tendency

AIM: It has been indicated that NPs may change the amyloidogenic steps of proteins and relevant cytotoxicity. Therefore, this report assigned to explore the impact of ZVFe NPs on the amyloidogenicity and cytotoxicity of α-synuclein as one of the many known amyloid proteins. METHODS: The characteriza...

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Detaylı Bibliyografya
Yayımlandı:Int J Nanomedicine
Asıl Yazarlar: Tahaei Gilan, Seyedeh Sahar, Yahya Rayat, Dorsa, Mustafa, Twana Ahmed, Aziz, Falah Mohammad, Shahpasand, Koorosh, Akhtari, Keivan, Salihi, Abbas, Abou-Zied, Osama K, Falahati, Mojtaba
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove 2019
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602305/
https://ncbi.nlm.nih.gov/pubmed/31417259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S212387
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