α-synuclein interaction with zero-valent iron nanoparticles accelerates structural rearrangement into amyloid-susceptible structure with increased cytotoxic tendency

AIM: It has been indicated that NPs may change the amyloidogenic steps of proteins and relevant cytotoxicity. Therefore, this report assigned to explore the impact of ZVFe NPs on the amyloidogenicity and cytotoxicity of α-synuclein as one of the many known amyloid proteins. METHODS: The characteriza...

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Dades bibliogràfiques
Publicat a:Int J Nanomedicine
Autors principals: Tahaei Gilan, Seyedeh Sahar, Yahya Rayat, Dorsa, Mustafa, Twana Ahmed, Aziz, Falah Mohammad, Shahpasand, Koorosh, Akhtari, Keivan, Salihi, Abbas, Abou-Zied, Osama K, Falahati, Mojtaba
Format: Artigo
Idioma:Inglês
Publicat: Dove 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602305/
https://ncbi.nlm.nih.gov/pubmed/31417259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S212387
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