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Yeast ceramide synthases, Lag1 and Lac1, have distinct substrate specificity
LAG1 was the first longevity assurance gene discovered in Saccharomyces cerevisiae. The Lag1 protein is a ceramide synthase and its homolog, Lac1, has a similar enzymatic function but no role in aging. Lag1 and Lac1 lie in an enzymatic branch point of the sphingolipid pathway that is interconnected...
Gardado en:
| Publicado en: | J Cell Sci |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Company of Biologists Ltd
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6602303/ https://ncbi.nlm.nih.gov/pubmed/31164445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.228411 |
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