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Differential Regulation of Ceramide Synthase Components LAC1 and LAG1 in Saccharomyces cerevisiae

In Saccharomyces cerevisiae, the essential ceramide synthase reaction requires the presence of one of a homologous pair of genes, LAG1 and LAC1. Mutants that lack both of these genes cannot produce ceramide and exhibit a striking synthetic growth defect. While the regulation of ceramide production i...

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Detalhes bibliográficos
Main Authors: Kolaczkowski, Marcin, Kolaczkowska, Anna, Gaigg, Barbara, Schneiter, Roger, Moye-Rowley, W. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC500886/
https://ncbi.nlm.nih.gov/pubmed/15302821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.3.4.880-892.2004
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