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Embryonic Cul4b is important for epiblast growth and location of primitive streak layer cells
Cul4b-null (Cul4b(Δ/)Y) mice undergo growth arrest and degeneration during the early embryonic stages and die at E9.5. The pathogenic causes of this lethality remain incompletely characterized. However, it has been hypothesized that the loss of Cul4b function in extraembryonic tissues plays a key ro...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6602292/ https://ncbi.nlm.nih.gov/pubmed/31260508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219221 |
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