ERK inhibition promotes neuroectodermal precursor commitment by blocking self-renewal and primitive streak formation of the epiblast

BACKGROUND: Pluripotent stem cells hold great promise for regenerative medicine. However, before clinical application, reproducible protocols for pluripotent stem cell differentiation should be established. Extracellular signal-regulated protein kinase (ERK) signaling plays a central role for the se...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Stem Cell Res Ther
Päätekijät: Yu, Yang, Wang, Xiaoxiao, Zhang, Xiaoxin, Zhai, Yanhua, Lu, Xukun, Ma, Haixia, Zhu, Kai, Zhao, Tongbiao, Jiao, Jianwei, Zhao, Zhen-Ao, Li, Lei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2018
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756365/
https://ncbi.nlm.nih.gov/pubmed/29304842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0750-8
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