LL-37 alone and in combination with IL17A enhances proinflammatory cytokine expression in parallel with hyaluronan metabolism in human synovial sarcoma cell line SW982—A step toward understanding the development of inflammatory arthritis

LL-37 is the only human cathelicidin-family host defense peptide and has been reported to interact with invading pathogens causing inflammation at various body sites. Recent studies showed high levels of LL-37 in the synovial-lining membrane of patients with rheumatoid arthritis, a common type of in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kuensaen, Chakkrapong, Chomdej, Siriwadee, Kongdang, Patiwat, Sirikaew, Nutnicha, Jaitham, Rungnaree, Thonghoi, Supitcha, Ongchai, Siriwan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602187/
https://ncbi.nlm.nih.gov/pubmed/31260471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218736
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