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Proinflammatory cytokines and lipopolysaccharides up regulate MMP-3 and MMP-13 production in Asian elephant (Elephas maximus) chondrocytes: attenuation by anti-arthritic agents

BACKGROUND: Osteoarthritis (OA), the most common form of arthritic disease, results from destruction of joint cartilage and underlying bone. It affects animals, including Asian elephants (Elephas maximus) in captivity, leading to joint pain and lameness. However, publications regarding OA pathogenes...

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Detalhes bibliográficos
Publicado no:BMC Vet Res
Main Authors: Sirikaew, Nutnicha, Chomdej, Siriwadee, Tangyuenyong, Siriwan, Tangjitjaroen, Weerapongse, Somgird, Chaleamchat, Thitaram, Chatchote, Ongchai, Siriwan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873576/
https://ncbi.nlm.nih.gov/pubmed/31752879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-019-2170-8
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