Proinflammatory cytokines and lipopolysaccharides up regulate MMP-3 and MMP-13 production in Asian elephant (Elephas maximus) chondrocytes: attenuation by anti-arthritic agents

BACKGROUND: Osteoarthritis (OA), the most common form of arthritic disease, results from destruction of joint cartilage and underlying bone. It affects animals, including Asian elephants (Elephas maximus) in captivity, leading to joint pain and lameness. However, publications regarding OA pathogenes...

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Publicado en:BMC Vet Res
Autores principales: Sirikaew, Nutnicha, Chomdej, Siriwadee, Tangyuenyong, Siriwan, Tangjitjaroen, Weerapongse, Somgird, Chaleamchat, Thitaram, Chatchote, Ongchai, Siriwan
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873576/
https://ncbi.nlm.nih.gov/pubmed/31752879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-019-2170-8
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