Proinflammatory cytokines and lipopolysaccharides up regulate MMP-3 and MMP-13 production in Asian elephant (Elephas maximus) chondrocytes: attenuation by anti-arthritic agents

BACKGROUND: Osteoarthritis (OA), the most common form of arthritic disease, results from destruction of joint cartilage and underlying bone. It affects animals, including Asian elephants (Elephas maximus) in captivity, leading to joint pain and lameness. However, publications regarding OA pathogenes...

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Bibliografski detalji
Izdano u:BMC Vet Res
Glavni autori: Sirikaew, Nutnicha, Chomdej, Siriwadee, Tangyuenyong, Siriwan, Tangjitjaroen, Weerapongse, Somgird, Chaleamchat, Thitaram, Chatchote, Ongchai, Siriwan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873576/
https://ncbi.nlm.nih.gov/pubmed/31752879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-019-2170-8
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