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Proinflammatory Effects of IL-1β Combined with IL-17A Promoted Cartilage Degradation and Suppressed Genes Associated with Cartilage Matrix Synthesis In Vitro

Combinations of IL-1β and other proinflammatory cytokines reportedly promote the severity of arthritis. We aimed to investigate the effects of IL-1β combined with IL-17A on cartilage degradation and synthesis in in vitro models. Cartilage explant degradation was determined using sulfated glycosamino...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Kongdang, Patiwat, Chokchaitaweesuk, Chatchadawalai, Tangyuenyong, Siriwan, Ongchai, Siriwan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6833041/
https://ncbi.nlm.nih.gov/pubmed/31614911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24203682
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