Live Imaging of Kv7.2/7.3 Cell Surface Dynamics at the Axon Initial Segment: High Steady-State Stability and Calpain-Dependent Excitotoxic Downregulation Revealed

The voltage-gated K(+) channels Kv7.2 and Kv7.3 are located at the axon initial segment (AIS) and exert strong control over action potential generation. Therefore, changes in their localization or cell surface numbers are likely to influence neuronal signaling. However, nothing is known about the ce...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Benned-Jensen, Tau, Christensen, Rasmus Kordt, Denti, Federico, Perrier, Jean-Francois, Rasmussen, Hanne Borger, Olesen, Søren-Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602044/
https://ncbi.nlm.nih.gov/pubmed/26888935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2631-15.2016
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