Astrocytic GAP43 Induced by the TLR4/NF-κB/STAT3 Axis Attenuates Astrogliosis-Mediated Microglial Activation and Neurotoxicity

Growth-associated protein 43 (GAP43), a protein kinase C (PKC)-activated phosphoprotein, is often implicated in axonal plasticity and regeneration. In this study, we found that GAP43 can be induced by the endotoxin lipopolysaccharide (LPS) in rat brain astrocytes both in vivo and in vitro. The LPS-i...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Hung, Chia-Chi, Lin, Chun-Hua, Chang, Hsuan, Wang, Chen-Yu, Lin, Shang-Hsuan, Hsu, Pei-Chien, Sun, Yu-Yo, Lin, Teng-Nan, Shie, Feng-Shiun, Kao, Lung-Sen, Chou, Chih-Ming, Lee, Yi-Hsuan
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2016
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602016/
https://ncbi.nlm.nih.gov/pubmed/26865625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3457-15.2016
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars