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Early Activation of STAT3 Regulates Reactive Astrogliosis Induced by Diverse Forms of Neurotoxicity

Astrogliosis, a cellular response characterized by astrocytic hypertrophy and accumulation of GFAP, is a hallmark of all types of central nervous system (CNS) injuries. Potential signaling mechanisms driving the conversion of astrocytes into “reactive” phenotypes differ with respect to the injury mo...

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Detalhes bibliográficos
Main Authors: O'Callaghan, James P., Kelly, Kimberly A., VanGilder, Reyna L., Sofroniew, Michael V., Miller, Diane B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098997/
https://ncbi.nlm.nih.gov/pubmed/25025494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102003
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