Dopamine D1-like Receptors Regulate Constitutive, μ-Opioid Receptor-Mediated Repression of Use-Dependent Synaptic Plasticity in Dorsal Horn Neurons: More Harm than Good?

The current study reports on a synaptic mechanism through which D1-like receptors (D1LRs) modulate spinal nociception and plasticity by regulating activation of the μ-opioid receptor (MOR). D1LR stimulation with agonist SKF 38393 concentration-dependently depressed C-fiber-evoked potentials in rats...

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Publicat a:J Neurosci
Autors principals: Aira, Zigor, Barrenetxea, Teresa, Buesa, Itsaso, García del Caño, Gontzal, Azkue, Jon Jatsu
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601769/
https://ncbi.nlm.nih.gov/pubmed/27194343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2469-15.2016
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