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Pin1 Modulates the Synaptic Content of NMDA Receptors via Prolyl-Isomerization of PSD-95

Phosphorylation of serine/threonine residues preceding a proline regulates the fate of its targets through postphosphorylation conformational changes catalyzed by the peptidyl-prolyl cis-/trans isomerase Pin1. By flipping the substrate between two different functional conformations, this enzyme exer...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Antonelli, Roberta, De Filippo, Roberto, Middei, Silvia, Stancheva, Stefka, Pastore, Beatrice, Ammassari-Teule, Martine, Barberis, Andrea, Cherubini, Enrico, Zacchi, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601765/
https://ncbi.nlm.nih.gov/pubmed/27194325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3124-15.2016
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