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PSD-95 and PKC converge in regulating NMDA receptor trafficking and gating

Neuronal NMDA receptors (NMDARs) colocalize with postsynaptic density protein-95 (PSD-95), a putative NMDAR anchoring protein and core component of the PSD, at excitatory synapses. PKC activation and PSD-95 expression each enhance NMDAR channel opening rate and number of functional channels at the c...

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Détails bibliographiques
Auteurs principaux: Lin, Ying, Jover-Mengual, Teresa, Wong, Judy, Bennett, Michael V. L., Zukin, R. Suzanne
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1750863/
https://ncbi.nlm.nih.gov/pubmed/17179037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609924104
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