Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors

Aberrant translation initiation at non-AUG start codons is associated with multiple cancers and neurodegenerative diseases. Nevertheless, how non-AUG translation may be regulated differently from canonical translation is poorly understood. Here, we used start codon-specific reporters and ribosome pr...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Genes Dev
Hlavní autoři: Kearse, Michael G., Goldman, Daniel H., Choi, Jiou, Nwaezeapu, Chike, Liang, Dongming, Green, Katelyn M., Goldstrohm, Aaron C., Todd, Peter K., Green, Rachel, Wilusz, Jeremy E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601509/
https://ncbi.nlm.nih.gov/pubmed/31171704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.324715.119
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky