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Repeat-Associated Non-AUG Translation and Its Impact in Neurodegenerative Disease
Nucleotide repeat expansions underlie numerous human neurological disorders. Repeats can trigger toxicity through multiple pathogenic mechanisms, including RNA gain-of-function, protein gain-of-function, and protein loss-of-function pathways. Traditionally, inference of the underlying pathogenic mec...
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| Publicado no: | Neurotherapeutics |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4391382/ https://ncbi.nlm.nih.gov/pubmed/25005000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-014-0292-z |
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