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Repeat-associated non-AUG (RAN) translation and other molecular mechanisms in Fragile X Tremor Ataxia Syndrome

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset inherited neurodegenerative disorder characterized by progressive intention tremor, gait ataxia and dementia associated with mild brain atrophy. The cause of FXTAS is a premutation expansion, of 55 to 200 CGG repeats localized withi...

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Detalhes bibliográficos
Publicado no:Brain Res
Main Authors: Glineburg, M. Rebecca, Todd, Peter K., Charlet-Berguerand, Nicolas, Sellier, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier/North-Holland Biomedical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010627/
https://ncbi.nlm.nih.gov/pubmed/29453961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2018.02.006
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