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RAN translation from antisense CCG repeats in Fragile X Tremor/Ataxia Syndrome
OBJECTIVE: Repeat associated non-AUG (RAN) translation drives production of toxic proteins from pathogenic repeat sequences in multiple untreatable neurodegenerative disorders. Fragile X-associated tremor/ataxia syndrome (FXTAS) is one such condition, resulting from a CGG trinucleotide repeat expans...
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| Publicado no: | Ann Neurol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5177492/ https://ncbi.nlm.nih.gov/pubmed/27761921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24800 |
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