FGFR(3S249C) mutation promotes chemoresistance by activating Akt signaling in bladder cancer cells

Fibroblast growth factor receptor 3 (FGFR3) is a high frequency mutant gene in bladder cancer (BCa) and has become a promising therapeutic target due to its involvement in cell proliferation and migration. However, whether and how FGFR3 mutations affects BCa cell chemosensitivity is unknown. The cur...

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Bibliografiske detaljer
Udgivet i:Exp Ther Med
Main Authors: Xie, Xina, Lin, Jiatian, Zhong, Yuantang, Fu, Mianheng, Tang, Aifa
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2019
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601368/
https://ncbi.nlm.nih.gov/pubmed/31316618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7672
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