LncRNA CDKN2B-AS1 stabilized by IGF2BP3 drives the malignancy of renal clear cell carcinoma through epigenetically activating NUF2 transcription

Because of the lack of sensitivity to radiotherapy and chemotherapy, therapeutic options for renal clear cell carcinoma (KIRC) are scarce. Long noncoding RNAs (lncRNAs) play crucial roles in the progression of cancer. However, their functional roles and upstream mechanisms in KIRC remain largely unk...

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發表在:Cell Death Dis
Main Authors: Xie, Xina, Lin, Jiatian, Fan, Xiaoqin, Zhong, Yuantang, Chen, Yequn, Liu, Kaiqing, Ren, Yonggang, Chen, Xiangling, Lai, Daihuan, Li, Xuyi, Li, Zesong, Tang, Aifa
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895987/
https://ncbi.nlm.nih.gov/pubmed/33608495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03489-y
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