Human ES-derived MSCs correct TNF-α-mediated alterations in a blood–brain barrier model

BACKGROUND: Immune cell trafficking into the CNS is considered to contribute to pathogenesis in MS and its animal model, EAE. Disruption of the blood–brain barrier (BBB) is a hallmark of these pathologies and a potential target of therapeutics. Human embryonic stem cell-derived mesenchymal stem/stro...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Fluids Barriers CNS
Main Authors: Ge, Shujun, Jiang, Xi, Paul, Debayon, Song, Li, Wang, Xiaofang, Pachter, Joel S.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600885/
https://ncbi.nlm.nih.gov/pubmed/31256757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-019-0138-5
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki