Appearance of claudin-5(+) leukocytes in the central nervous system during neuroinflammation: a novel role for endothelial-derived extracellular vesicles

BACKGROUND: The mechanism of leukocyte transendothelial migration (TEM) across the highly restrictive blood-brain barrier (BBB) remains enigmatic, with paracellular TEM thought to require leukocytes to somehow navigate the obstructive endothelial tight junctions (TJs). Transient interactions between...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Paul, Debayon, Baena, Valentina, Ge, Shujun, Jiang, Xi, Jellison, Evan R., Kiprono, Timothy, Agalliu, Dritan, Pachter, Joel S.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112695/
https://ncbi.nlm.nih.gov/pubmed/27852330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0755-8
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