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Beyond the seed: structural basis for supplementary microRNA targeting by human Argonaute2
microRNAs (miRNAs) guide Argonaute proteins to mRNAs targeted for repression. Target recognition occurs primarily through the miRNA seed region, composed of guide (g) nucleotides g2–g8. However, nucleotides beyond the seed are also important for some known miRNA–target interactions. Here, we report...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6600645/ https://ncbi.nlm.nih.gov/pubmed/31268608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101153 |
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