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IDH1(R132H) Causes Resistance to HDAC Inhibitors by Increasing NANOG in Glioblastoma Cells
The R132H mutation in isocitrate dehydrogenase 1 (IDH1(R132H)) is commonly observed and associated with better survival in glioblastoma multiforme (GBM), a malignant brain tumor. However, the functional role of IDH1(R132H) as a molecular target for GBM treatment is not completely understood. In this...
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| 出版年: | Int J Mol Sci |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6600637/ https://ncbi.nlm.nih.gov/pubmed/31151327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20112679 |
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