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IDH1(R132H) Causes Resistance to HDAC Inhibitors by Increasing NANOG in Glioblastoma Cells
The R132H mutation in isocitrate dehydrogenase 1 (IDH1(R132H)) is commonly observed and associated with better survival in glioblastoma multiforme (GBM), a malignant brain tumor. However, the functional role of IDH1(R132H) as a molecular target for GBM treatment is not completely understood. In this...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6600637/ https://ncbi.nlm.nih.gov/pubmed/31151327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20112679 |
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