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IFN-γ and TNF-α aggravate endothelial damage caused by CD123-targeted CAR T cell
Background: CD123-targeted chimeric antigen receptor (CAR) T cell (CART123) for the treatment of acute myeloid leukemia (AML) and blastic plasmacytoid dendritic cell neoplasm has exhibited potential in clinical trials. However, capillary leakage syndrome, which is associated with endothelial cells d...
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| Publicat a: | Onco Targets Ther |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Dove
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6600319/ https://ncbi.nlm.nih.gov/pubmed/31417286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S205678 |
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