Suppression of Choroidal Neovascularization and Fibrosis by a Novel RNAi Therapeutic Agent against (Pro)renin Receptor

The receptor-associated prorenin system refers to the pathogenic mechanism whereby prorenin binding to (pro)renin receptor [(P)RR] dually activates the tissue renin-angiotensin system (RAS) and RAS-independent signaling, and its activation contributes to the molecular pathogenesis of various ocular...

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Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Liu, Ye, Kanda, Atsuhiro, Wu, Di, Ishizuka, Erdal Tan, Kase, Satoru, Noda, Kousuke, Ichihara, Atsuhiro, Ishida, Susumu
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599885/
https://ncbi.nlm.nih.gov/pubmed/31254924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.05.012
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