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Blockade of Platelet-Derived Growth Factor Signaling Inhibits Choroidal Neovascularization and Subretinal Fibrosis in Mice

Neovascular age related macular degeneration (nAMD) leads to severe vision loss worldwide and is characterized by the formation of choroidal neovascularization (CNV) and fibrosis. In the current study, we aimed to investigate the effect of blockade for platelet derived growth factor receptor-β (PDGF...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Liu, Ye, Noda, Kousuke, Murata, Miyuki, Wu, Di, Kanda, Atsuhiro, Ishida, Susumu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408710/
https://ncbi.nlm.nih.gov/pubmed/32679740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9072242
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