(Pro)renin Receptor Promotes Choroidal Neovascularization by Activating Its Signal Transduction and Tissue Renin-Angiotensin System

The receptor-associated prorenin system (RAPS) refers to pathogenic mechanisms whereby prorenin binding to its receptor activates both the tissue renin-angiotensin system (RAS) and RAS-independent intracellular signaling pathways. Although we found significant involvement of angiotensin II type 1 re...

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Autors principals: Satofuka, Shingo, Ichihara, Atsuhiro, Nagai, Norihiro, Noda, Kousuke, Ozawa, Yoko, Fukamizu, Akiyoshi, Tsubota, Kazuo, Itoh, Hiroshi, Oike, Yuichi, Ishida, Susumu
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2008
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626401/
https://ncbi.nlm.nih.gov/pubmed/18974301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080457
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