Interleukin-6 Receptor-Mediated Activation of Signal Transducer and Activator of Transcription-3 (STAT3) Promotes Choroidal Neovascularization

Interleukin (IL)-6, a potent proinflammatory cytokine, is suggested to be a risk factor for choroidal neovascularization (CNV) because of its increased levels in the serum of patients with age-related macular degeneration; however, the role of IL-6 in CNV has not been defined. The present study reve...

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Hauptverfasser: Izumi-Nagai, Kanako, Nagai, Norihiro, Ozawa, Yoko, Mihara, Masahiko, Ohsugi, Yoshiyuki, Kurihara, Toshihide, Koto, Takashi, Satofuka, Shingo, Inoue, Makoto, Tsubota, Kazuo, Okano, Hideyuki, Oike, Yuichi, Ishida, Susumu
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2007
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Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899441/
https://ncbi.nlm.nih.gov/pubmed/17525280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061018
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