Negative regulation of miR‐1275 by H3K27me3 is critical for glial induction of glioblastoma cells

Activation of the cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathway induces glial differentiation of glioblastoma (GBM) cells, but the mechanism by which microRNA (miRNA) regulate this process remains poorly understood. In this study, by performing miRNA genomics and loss‐ and gain‐...

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Vydáno v:Mol Oncol
Hlavní autoři: Mai, Jialuo, Gu, Jiayu, Liu, Ying, Liu, Xincheng, Sai, Ke, Chen, Zhijie, Lu, Wanjun, Yang, Xiaozhi, Wang, Jingyi, Guo, Cui, Sun, Shuxin, Xing, Fan, Sheng, Longxiang, Lu, Bingzheng, Zhu, Zhu, Sun, Hongjiaqi, Xue, Dongdong, Lin, Yuan, Cai, Jing, Tan, Yaqian, Li, Chuntao, Yin, Wei, Cao, Lin, Ou‐yang, Ying, Qiu, Pengxin, Su, Xingwen, Yan, Guangmei, Liang, Jiankai, Zhu, Wenbo
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599839/
https://ncbi.nlm.nih.gov/pubmed/31162799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12525
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