The Anti-Warburg Effect Elicited by the cAMP-PGC1α Pathway Drives Differentiation of Glioblastoma Cells into Astrocytes

Glioblastoma multiforme (GBM) is among the most aggressive of human cancers. Although differentiation therapy has been proposed as a potential approach to treat GBM, the mechanisms of induced differentiation remain poorly defined. Here, we established an induced differentiation model of GBM using cA...

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Publicado no:Cell Rep
Main Authors: Xing, Fan, Luan, Yizhao, Cai, Jing, Wu, Sihan, Mai, Jialuo, Gu, Jiayu, Zhang, Haipeng, Li, Kai, Lin, Yuan, Xiao, Xiao, Liang, Jiankai, Li, Yuan, Chen, Wenli, Tan, Yaqian, Sheng, Longxiang, Lu, Bingzheng, Lu, Wanjun, Gao, Mingshi, Qiu, Pengxin, Su, Xingwen, Yin, Wei, Hu, Jun, Chen, Zhongping, Sai, Ke, Wang, Jing, Chen, Furong, Chen, Yinsheng, Zhu, Shida, Liu, Dongbing, Cheng, Shiyuan, Xie, Zhi, Zhu, Wenbo, Yan, Guangmei
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926788/
https://ncbi.nlm.nih.gov/pubmed/28076790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.037
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