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Human Primary Cell-Based Organotypic Microtissues for Modeling Small Intestinal Drug Absorption

PURPOSE: The study evaluates the use of new in vitro primary human cell-based organotypic small intestinal (SMI) microtissues for predicting intestinal drug absorption and drug-drug interaction. METHODS: The SMI microtissues were reconstructed using human intestinal fibroblasts and enterocytes cultu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharm Res
Prif Awduron: Ayehunie, Seyoum, Landry, Tim, Stevens, Zachary, Armento, Alex, Hayden, Patrick, Klausner, Mitchell
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599640/
https://ncbi.nlm.nih.gov/pubmed/29476278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-018-2362-0
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